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Prima pagina arrow Produse arrow Detoxificare organism arrow Calciu D-Glucarate 200 mg - 60 capsule

Calciu D-Glucarate 200 mg - 60 capsule




 Comandati online
Producator:
Pret: 74.43 LEI (tva inclus)

 


Livrare prin Posta Romana (2-4 zile) Pret: 10 lei
Livrare prin Curierat Rapid (24 ore) Pret: 20 lei

 Comandati telefonic Calciu D-Glucarate 200 mg - 60 capsule:

RDS: 0368/800.109
Romtelecom: 0268/418.667
Vodafone: 0723.333.505
Orange:    0747.379.988

 Descriere Calciu D-Glucarate 200 mg - 60 capsule:


CALCIUM D-GLUCARAT - 200 mg - 60 cps.

Anticancerigen, antitumoral, antimetastatic, detoxifiant

Calciul D-Glucarat este sarea calcic? a Acidului D-Glucaric, o substanta produsa natural de catre mamifere inclusiv de om, dar in cantitati extrem de mici. Este insa substanta care ajuta organismul sa elimine toxinele, in special cele carcinogene. Suplimentarea pe cale orala cu Calciu D-Glucarat inhiba beta-glucuronidaza, o enzima produsa de microflora din colon si care este implicata in faza II de detoxificare a ficatului. Prezenta in exces a beta-glucuronidazei este legata direct de riscurile marite de aparitie a cancerelor cum ar fi cancerul la colon, san, prostata. Un alt aspect benefic a suplimentarii cu Calciu D-Glucarat este reglarea metabolismului estrogenului (prin eliminarea excesului de estrogen din ficat) si reducerea nivelului de lipide, efect foarte important in special pentru femei.

Pe scurt, Calciu D-Glucarat micsoreaza nivelul de glucuronidaza si prin aceasta permite organismului sa elimine carcinogenii (substante chimice care cauzeaza cancer). Eliminarea carcinogenilor se face, in special prin fecale, prin urmare este nevoie de un colon curat in vederea tranzitarii rapide a toxinelor carcinogene si eliminarea rapida prin fecale (nota: pentru curatirea colonului avem in farmacie produsul CURATITOR COLON)

In anul 1990, Dr.Walaszek (descoperitorul efectelor D-Glucaratului) s-a mutat la Centrul de Carcinogeneza MD Anderson din Houston Texas, unde si-a continuat cercetarile. In mai multe articole publicate anterior el arata ca aceasta substantareduce "proliferarea" tumorilor. Cu alte cuvinte prezenta aceastui agent opreste sau incetineste cresterea tumorilor. In 1991, 1992, 1993 si 1994 echipa Dr. Walaszek a efectuat mai multe teste atat pe animale, cat si pe oameni, demonstrand ca doze mici de Calciu D-Glucarat administrate oral sunt convertite imediat in D-Glucaro-lactona care conduce la o activitate anti-tumoralamarita a rentinoidelor.
Tehnologia de extragere si purificare a Calciului D-Glucarat este patentata in Statele Unite.
Se integreaza, de asemenea, in diferite protocoale in cazurile de cancer, in special la san, colon si prostata.

 

Compozitie

Fiecare capsula contine:

Calciu D-Glucarat 200 mg


Nu contine: lactate, ou, conservanti artificiali, coloranti, fermenti, indulcitori artificiali, grau, soia sau porumb.

 

Administrare

 

Modul recomandat de administrare (doar pentru adulti): 1-2 capsule pe zi cu minim 30 minute inainte de mese.

Atentionari

  • - Nu se recomanda gravidelor si femeilor care alapteaza!

 

Bibliografie

1. Walaszek, Z., Hanausek, M., Szemraj, J., and Adams, A.K. 1998, D-Glucarate acid as a prospective tumor marker. Meth. Mol. Med., 14, 487-495.

2. Walaszek, Z., Szemraj, J., Adams, A.K., and Hanausek, M. 1992, Reduced levels of D-Glucaric acid in mammary tumor-bearing hosts and the effect of its supplementation during estrogen replacement and tamoxifin therapy. Proc. Am. Assoc. Cancer Res. 37: 183.

3. Heerdt, A.S., Young, C.W.., and Borgen, P.I., 1995, Calcium Glucarate as a chemopreventative agent in breast cancer., Isr. J. Med. Sci. 31: 101-105.

4. Walaszek, Z. Chemopreventative properties of D-Glucaric acid derivatives. Cancer Bull 1993; 45: 453-457.

5. Walaszek, Z., Szemraj, J., Adams, A.K., Kordari, P., and Hanausek, M. 1992, Reduced levels of D-Glucaric acid in mammary tumor-bearing Host. Breast Cancer Res. Treat., 375: 108.

6. Walaszek, Z., Hanausek, M., Adams, A.K. and Sherman, U. 1991, Cholesterol lowering effects of dietary D-Glucarate. Faseb J., 5: A930.

7. Walaszek, Z., Hanausek, M., Sherman, U. and Adams, A.K. 1990, Antiproliferative effect of dietary glucarate on the Sprague Dawley in rat mammary gland. Cancer Lett. 49: 51-57.

8. Walaszek, Z., Adams, A.K., Sherman, U., Viaje, A., Rotstein, J.B., Hanausek, M. and Slaga, T.J. 1990, Antiproliferate effects of Calcium D-Glucarate (CG) and D-glucaro-1,4-lactone (GL) on the rat mammary gland, colon and mouse skin. Proc. Am. Assoc. Cancer Res., 31: 124.

9. Walaszek, Z. 1990, Potential use of D-Glucarate acid derivatives in cancer prevention. Cancer Lett. 54: 1-8.

10. DiGiovanni, J., 1990, Inhibition of chemical carcinogenesis. In: Chemical Carcinogenesis and Mutagenesis II, Cooper, C.S. and Grover, P.L. (eds.), Springer Verlag, Berlin, pp. 159-224.

11. Walaszek, Z., Adams, A.K., and Flores, F., 1989, Inhibition of 7,12-dimethylbenz(a)-anthracene(DMBA)-induced rat mammary carcinogenesis by glucarate. Proc. Am. Assoc. Cancer Res., 30: 170.

12. Abbou-Issa, H., Koolemans-Beynen, A., Minton, J.P. and Webb, T.E., 1989, Synergistic interaction between 13-cis-retinoic acid and glucarate: activity against rat mammary tumor induction and MCF-7 cells. Biochem. Biophys. Res. Commun.,163: 1364-1369.

13. Dwivedi, C., Oredipe, O.A., Barth, R.F., Downie, A.A. and Webb, T.E., 1989, Effects of the experimental chemopreventative agent, glucarate on intestinal carcinogenesis in rats. Carcinogenesis, 10: 1539-1541.

14. Oredipe, O.A., Barth, R.F., Dwivedi, C. and Webb, T.E., 1989, Chemopreventative activity of dietary glucarate on azoxymethane-induced altered hepatic loci in rats. Res. Commun. Chem. Pathol. Pharmacol., 65: 345-359.

15. Dwivedi. C., Downie, A.A. and Webb, T.E., 1989, Modulation of chemically initiated and promoted skin tumorigenesis in CD-1 mice by dietary glucarate. J. Environ. Path. Toxicol. Oncol., 9: 253-259.

16. Walaszek, Z., Hanausek, M., Sherman, U., Del Rio, M. and Adams, A.K., 1989, Effects of (+) glucaric acid derivatives and tamoxifen on human breast cancer cells (MCF-7). Breast Cancer Res. Treat., 14: 175.

17. Walaszek, Z., Flores, F. and Adams, A.K., 1988, Effect of dietary glucarate on estrogen receptors and growth of 7,12-dimethylbenz[a] anthracene-induced rat mammary carcinomas. Breast Cancer Res. Treat., 12: 128.

18. Walaszek, Z., Hanausek-Walaszek, M. and Webb, T.E., 1988, Repression by sustained release or glucuronidase inhibitors of chemical carcinogen-mediated induction of a marker oncofetal protein in rodents. J. Toxicol. Environ. Health, 23: 15-27.

19. Abbou-Issa, H.M., Duruibe, V.A., Minton, J.P., Larroya, S., Dwivedi, C., and Webb, T.E., 1988, Putative metabolites derived from dietary combinations of calcium glucarate and N-(4hydroxypheny)retinamide act synergistically to inhibit the induction of rat mammary rumors by 7,12-dimethylbenz[a]-anthracene. Proc. Natl. Acad. Sci. USA. 85: 4181-4184.

20. Oredipe, O.A., Barth, R.F., Hanausek-Walaszek, M., Sautins, I., Walaszek, Z. and Webb, T.E. 1987, Effects of an inhibitor of B-glucuronidase on hepatocarcinogenesis. Proc. Am. Assoc. Cancer Res., 28: 156.

21. Oredipe, O.A., Barth, R.F., Hanausek-Walaszek, M., Sautins, I. Walaszek, Z. and Webb, T.E. 1987, Effects of calcium glucarate on the promotion of diethylnitrosamine-initiated altered hepatic loci in rats. Cancer. Lett., 38, 95-99.

22. Walaszek, Z., Hanausek-Walaszek, M., Minton, J.P. and Webb, T.E. 1986, Dietary glucarate as antipromoter of 7,12-dimethylbenz[a]-anthra-cene-induced mammary tumorigenesis. Carcinogenesis, 7:1463-1466.

23. Minton, J.P., Walaszek, Z., Hanausek-Walaszek, M., and Webb, T.E. 1986, B-Glucuronidase levels in patients with fibrocystic breast disease. Breast Cancer Res. Treat., 8: 217-222.

24. Walaszek, Z., Hanausek-Walaszek, M., Webb, T.E., 1986, Dietary glucarate-mediated reduction of sensitivity of murine strains to chemical to chemical carcinogenesis. Cancer Lett., 33: 25-32.




 

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